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Mechanistic target of rapamycin complex 1 (mTORC1) detects the concentration of cysteine via the small G protein Recombination activating gene (Rag) and positively regulates the translation and expression of GPX4 protein by phosphorylating eukaryotic initiation factor 4E-binding proteins (4EBPs)

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This maintains the weekly rhythm while allowing the previous medication to clear