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So this is sort of like a broadly applicable rule of thumb until you get to the question of, well, does that mean that you eat three square meals a day and no snacking, or does that mean that you eat one meal a day

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The rat liver enzyme catalyzes the reductive dehalogenation of o -chloroacetophenone, but not of benzyl halides, suggesting the need for the carbonyl to stabilize a carbanion intermediate (Kitada et al., 1985)