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Therefore, issues regarding the establishment of standardized techniques for sentinel node mapping and detection, as well as oncologic safety, must be resolved

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But for patients who are concomitantly using a strong CYP2D6 inhibitor such as quinidine, paroxetine, fluoxetine, or bupropion or having the CYP2D6 poor metabolizer phenotype should not take more than 36 mg per day, with a maximum of 18 mg each dosage (García-González et al