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The highly conserved active site (–Cys–Gly–Pro–Cys–), and the two cysteine residues at positions 32 and 35 are responsible for the disulphide reductase activity of Trx1 by reducing disulphide bonds on target proteins to form free thiol groups [11] (Figure 4)

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For general use, one 300mg pill once per week is often suggested