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Mechanistically, SETDB1 suppresses EMT by promoting H3K9me3 at the SNAI1 locus, whereas USP2 activates TGFβ signaling through deubiquitination/stabilization of TGFβR1 (via TXNDC5) and enhances ferroptosis by deubiquitinating TFRC

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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Rice M.E., Russo-Menna I

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