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* Entries in each column identified by a, b, c, d differ significantly (Duncan's multiple-range test, P 15mm in diameter on ultrasound (28)

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The carbohydrate-insulin model—a special case of the metabolic paradigm The CIM represents an opposing paradigm, with origins in the early twentieth century [7, 21,22,23,24,25,26,27,28], that considers the supply of metabolic fuels in the blood (as proxy for fuel oxidation) the regulated parameter