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KLOW peptide exhibits a plasma half-life of approximately 6–8 hours following subcutaneous injection, with complete plasma clearance occurring within 24–48 hours in most research models

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We also found that auranofin is an efficient inhibitor of pure TGR ( K i = 10 nM), able to kill parasites rapidly in culture at physiological concentrations (5 μM), and able to partially cure infected mice (worm burden reductions of ~60%)