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The primary reasons for the low productivity of the producing strains that are now available are the inhibition of the cbi operon and cysG by the cobalamin riboswitch and other downregulating mechanisms

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Antibody-conjugated beads were then incubated (12 h, 4 °C) with purified α5β1 and αvβ3 integrin proteins (Yo proteins AB, Huddinge, Sweden)

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