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35 (7), e21707 (2021)

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Size:Box of 25x30 ml vials

Thrombotic thrombocytopenic purpura is characterized by ADAMTS-13 deficiency, resulting in a deficient excision of the ultra-large VWF multimers presented in the VWF molecule on ECs, causing platelet adhesion and aggregation with rapid generation of disseminated microthrombi