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Specific Improvements: Cagrilintide suppresses the nuclear factor-kappa B (NF-κB) pathway, reducing the synthesis and release of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6)

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All positively stained cells were counted and the “% Nissl positive neuron” was calculated by dividing the number of positive neurons by the total number of neurons in each cell [1]