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In particular, cAMP-specific PDE4 type is widely present in immune cells including neutrophils and contributes to neutrophil-mediated lung inflammation (Phillips, 2020), apremilast for psoriasis (Queiro Silva et al., 2020), and crisaborole for atopic dermatitis (Singh et al., 2019), and ensifentrine (RPL554, NCT04027439 for COPD) (Phillips, 2020)

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Quantity:5 Ampoules (half kit)

8 This effect increased with duration of therapy, and patients had an unclear prophylactic supplementation response