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The pathogenesis of ALD involves multiple interconnected aging-related processes, including oxidative stress, inflammation, and mitochondrial dysfunction, all of which are regulated by SIRT1, a key modulator of cellular stress responses (Ramirez et al., 2017)

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[DOI] [PubMed] [Google Scholar] 50.Perumal N., Nallappan M., Shohaimi S., Kassim N.K., Tee T.T., Cheah Y.H