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The findings showed that 2.4 mg each of semaglutide and cagrilintide resulted in a 23% reduction in body weight, whereas 15 mg of tirzepatide resulted in a 25.5% reduction

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The local inflammatory microenvironment in the ovary, characterized by elevated levels of pro-inflammatory cytokines such as IL-18 and IL-1β, impairs the function of follicular granulosa cells and accelerates follicular atresia, ultimately contributing to polycystic-like morphological changes in the ovary (62)

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