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For example, the upregulation of the mitogen-activated protein kinases (MAPK) pathway, and phosphoinositide 3-kinases, protein kinase B, mammalian target of rapamycin (PI3K/AKT/mTOR) pathways through the inhibition of tuberous sclerosis complex proteins (TSC1 and TSC2) drive aerobic glycolysis and cell cycle progression

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Decrease of CMV and HSV6 load on PB was documented in 4 out of 7 pts, suggesting a potential activity also on viruses other than AdV