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Then bedding was exchanged only between mice of the same genotypes twice a week for the remaining 5 weeks before the beginning of treatment [due to the known differences in microbiome between APOE-TR mice (Tran et al., 2019)]

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3 ELISA fMPOa, ELISA fMPOp, and CM-S fMPOa showed good discriminatory ability in differentiating between remission-mild and moderate-severe, or inactive and active ulcerative colitis (Figure 5A and C) and Crohn’s disease (Figure 5B and D, Table 2)