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[0707] In some embodiments, the administration of the polynucleotide encoding a lysosomal enzyme in combination with a pharmacological chaperone or glucosylceramide synthase inhibitor of the invention results in expression of lysosomal enzyme in at least some of the cells of a subject that persists for a period of time sufficient to allow significant metabolism of accumulated undegraded metabolite in lysosomes to occur

Fat Oxidation

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What Should You Expect, and When