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These effects were accompanied by restoration of ATP levels, enhanced nitric oxide (NO) production, increased platelet endothelial cell adhesion molecule-1 (CD31) and phosphorylated-endothelial nitric oxide synthase (eNOS) levels, and suppression of interleukin-1β (IL-1β), interleukin-6 (IL-6), and interleukin-18 (IL-18)