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Moreover, this study suggested that these anti-neuroaging gene effects of melatonin are possibly mediated by neuropeptide Y (Jenwitheesuk et al., 2017, 2018)

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This finding provides a possible explanation for the in vivo demonstration that LASSS pre-administration prevents nitration of extracellular HGF during 5-days muscle disuse (without LASSS supplementation during disuse) while the control GSSSG pre-administration does not