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Testosterone upregulates the expression of mitochondrial ND1 and ND4 and alleviates the oxidative damage to the nigrostriatal dopaminergic system in orchiectomized rats

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Collectively, we have shown using both a small animal rat model and a large animal cynomolgus monkey model that fibroblast therapy can be used to maintain the IVD height and the biomechanical properties of degenerative IVDs