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In addition to MNAM and NNMTi, three new NAM analog inhibitors were reported for the treatment of MetS-related disorders in animal models: JBSNF-000088 (Kannt et al., 2018), JBSNF-000265 (Ruf et al., 2018), and JBSNF-000028 (Ruf et al., 2022)

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The research highlights how disrupting bacterial metabolism can help the body better tolerate infection and heal more effectively