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Manual acupuncture (MA) at Baihui (GV20), Yintang (GV29) and ST36 can also effectively alleviate the destruction of the intestinal mucosal barrier, manifested as orderly arrangement of intestinal gaps and narrow connecting gaps ( 4.2 Regulating the structure of gut microbiota and metabolic pathways Acupuncture treatment modulates the species abundance of the gut microbiota