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The Smad signaling cascade, initiated by TGF-β stimulation, involves the phosphorylation of receptor-associated Smads, their complex formation with common-mediator Smads, and subsequent nuclear translocation to regulate the transcription of fibrosis-related genes (123, 124)

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Protective effects of lycium barbarum polysaccharides on blood-retinal barrier via ROCK1 pathway in diabetic rats