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Nevertheless, the alcoholic lungs in ethanol-fed animal models are under increased oxidative stress, have altered nitric oxide metabolism, express abnormal amounts of transforming growth factor TGF-β, and are in a chronic proinflammatory state, with up-regulated expressions of IL-1β and tumor necrosis factor TNF-α

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10.1038/35012636 Nature 63 LiG.LiuT.KongX.WangL.JinX

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