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Building on the strategy of reinforcing protein tertiary structures via crosslinking with C3-symmetric triselectrophiles, Grossman and coworkers extended the concept to trimeric protein complexes using biocompatible, multivalent modifiers to obtain protein assembly with bicyclic topology and enhanced resistance to both thermal and chemical stress 54

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Biofilms, which are complex networks of pathogens encased within protective extracellular polymeric substances [24], play a pivotal role in the persistence of postoperative symptoms and ongoing mucosa inflammation and infections