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By month five, I honestly couldn't tell if it was still doing anything, but I was afraid to stop." His prescriber had him pull labs, take eight weeks off, and reassess

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Furthermore, when we cocultured T cells with BMDMs from mice deficient in MyD88/TRIF (downstream of TLR signaling) or TFEB (key regulator of lysosomal biogenesis), there was diminished T cell proliferation (Figure 6G)