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Liver-nervous system axis: pathways, dysregulation, and translational perspectives | Journal of Neuroinflammation | Springer Nature Link

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these include increasing cytosolic calcium concentrations, decreasing high-energy phosphate levels and activating AMP-activated protein kinase (AMPK), stimulating the adrenergic system that synthesizes cyclic adenosine monophosphate (c-AMP), and activating protein kinase A and other kinases, including mitogen activated protein kinase (MAPK) [90]