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Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment | npj Aging

For instance, vitamin B5 accumulated in MYC-overexpressing mammary tumors, where its conversion to coenzyme A fuels the tricarboxylic acid cycle, promoting tumor growth 3

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In the aging brain, the decline in proteostasis is associated with the accumulation of damaged proteins, leading to synaptic dysfunction and neuronal degeneration [111]