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Several pregnancy-associated proteins, including pregnancy-associated plasma protein A (PAPP-A), placental growth factor (PlGF), and annexin A5 (ANXA5), have been reported to bereduced in RPL cohorts, suggesting potential disruption of trophoblast function and immune-vascular regulation ( Beyond biomarker discovery, proteomic and metabolomic signatures suggest coordinated immune–metabolic reprogramming at the maternal–fetal interface

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There’s also niacinamide in there (aka vitamin B3, aka skin’s best friend) for brightening and barrier repair, and a mix of collagen, ceramides and even probiotics to keep your skin hydrated and happy