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JAMA Neurol 72(11):1324–1333 [DOI] [PubMed] [Google Scholar] Cummings JL, Atri A, Feldman HH, Hansson O, Sano M, Knop FK et al (2025) Evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic alzheimer’s disease

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In turn, methionine metabolism influences gut health, as evidenced by the interactions between methionine levels, microbial composition and disease states