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Depression Late-life depression is a common disorder sometimes occurring after acute illnesses, such as hip fracture or stroke (71, 72)

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Caspase 1 subsequently cleaves Pro-IL-1β and gasdermin D (GDDMD), resulting in N-GSDMD, which, after oligomerization in the cell membrane, leads to the formation of pores and the release of intracellular contents 61 (Fig