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Both αvβ6 and αvβ8 integrins facilitate TGFβ activation by interacting with the RGD sequence present in the latent, inactive LAP (latency-associated peptide)-TGFβ complex

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A case series published by Gershanik and colleagues in Pediatrics (1982) documented a serious and sometimes fatal toxicity syndrome in neonates receiving medications preserved with benzyl alcohol