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Fisetin upregulated the expression of endothelial nitric oxide synthase (eNOS) and Bcl-2, while downregulating the expression of caspase-3, microtubule-associated protein 1 light chain 3 (LC3), C/EBP homologous protein (CHOP), and TNF-α, thereby promoting structural and functional recovery in vascular and neuronal tissues [85]

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doi: 10.1007/s00125-014-3194-z 118 KowluruR