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doi: 10.3945/ajcn.114.086918 Summary Keywords nutritional interventions, osteoarthritis, metabolism, inflammation, oxidative stress, gut-joint axis Citation Wang Y, Cao Z, Gao Y, Shao P, Gao S, Dong M, Tian Z, Feng Y, Xu J and Xiang C (2025) Nutritional interventions for osteoarthritis: targeting the metabolism-inflammation-oxidative stress axis—clinical evidence and translational practice