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Its withdrawal accelerates dopaminergic neuronal degeneration, weakening reward circuitry and impairs serotonin (5-HT) synthesis and reuptake, particularly during the night, contributing to vasomotor symptoms such as hot flashes and nocturnal sweats (58,59)

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Choroid plexus of the fourth ventricle: Review and anatomic study highlighting anatomical variations, J Clin Neurosci, 2016, 26:79-83 Tubbs RS, Yan H, Demerdash A, Chern JJ, Fries FN, Oskouian RJ, Oakes WJ

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