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Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia

Cellular Uptake

Flavor:Strawberry Lime

Consistent with increased staining for the surface expression of CD80, I148M oe M1 macrophages showed significant upregulation of TLR4 (+24.5%), IL-1β (+446%), and IL-6 (+24%) compared to WT oe