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[2] Collins, C. B., Riskowski, R. A., Ackerson, C.J. Radiofrequency remote control of thermolysin activity. Sci Rep 2021 Mar 16;11(1):6070. doi: 10.1038/s41598-021-85611-w

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If the decision is made to use Topiramate, you should use effective birth control (contraception) unless you are planning to become pregnant