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PEG-MGF (pegylated mechano growth factor) is a synthetic peptide corresponding to the C-terminal E-domain of mechano growth factor (MGF), a splice variant of insulin-like growth factor-1 (IGF-1, designated IGF-1Ec)

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Under fasting or stress conditions, TECs utilize lactate as primary substrate for gluconeogenesis, which maintains systemic glucose homeostasis by coordinating with glucose reabsorption