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Symptoms of liver disease can include: Chronic fatigue Yellowing of the skin and eyes Swollen abdomen Pain in the upper right abdomen Lack of appetite Weight loss Dark colored urine Light colored stools Nausea Bruising Swollen legs Skin irritation Confusion (in late stage liver disease) If any of the above symptoms are present, along with any abnormal blood tests, medical attention should be sought immediately

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These findings were consistent with the network meta‐analysis estimates, which are presented in Figure 3B, and Supplement 7.2