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From the selected studies, the following data were extracted: first author’s name, publication year, sample size, study location, mean age of participants, intervention (type, dose, and duration of supplementation), study design and end-point values (as means and sd) for the number of follicles, endometrial thickness, TT, progesterone, serum LH levels, serum FSH levels, E2 and SHBG in both intervention and control groups

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How to pharmacologically target the circadian clock in a cell-type-specific manner from a systemic level needs to be further investigated