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[DOI] [PMC free article] [PubMed] [Google Scholar] Paszkiewicz G, Gualberto JM, Benamar A, Macherel D, Logan DC

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Genetic variants in the GIPR (rs1800437), and FTO (rs9939609) genes affect receptor density and signaling strength, meaning some people respond robustly to tirzepatide while others require higher doses or respond more slowly