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The Role of NAD+ in Regenerative Medicine - PMC

3.6 The altered glutathione S-transferase activity in Jin A-CMS Compared with the maintainer line, the Jin A-CMS line exhibited reduced GST ( Figure 12 ) and DHAR activity ( Figure 12 3.7 Changes of antioxidant enzymes in GhGPX4 silenced cotton and overexpressed Arabidopsis Results of the antioxidant enzyme activities and stress-related indicators in transgenic plants revealed that antioxidant enzyme activities (GST, DHAR, POD, CAT) in GhGPX4 silenced cotton decreased, accompanying the levels of MDA were elevated ( Figures 13a–f )

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Research has established that persistent activation of the PI3K-AKT-mTOR cascade markedly increases tumor cell resistance to both oxidative stress and ferroptosis