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38 Other toxins that are believed to play a role in HE are endogenous benzodiazepines, GABA, tryptophan, glutamine, serotonin, mercaptans, indoles, and skatoles.4, 34, 39 Hyperammonemia also leads to impaired glial function through increased intracellular glutamine concentration

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an important regulatory protein in the ERS process (304)] expression at both mRNA and protein levels