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The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting | Nature Reviews Immunology

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5-HTP also suppresses inflammation and arthritis through decreasing the production of pro-inflammatory mediators [102] and the antihistaminic drugs chloropyramine and, more strongly, chlorpheniramine potentiates the action of 5-HTP by inhibiting serotonin uptake [103]