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Del Prato S, Kahn SE, Pavo I, Weerakkody GJ, Yang Z, Doupis J, et al

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Figure 6 Klotho Regulation and GH Secretion To date, it has not been clearly established how klotho secretion is regulated, although the fact that the kidneys are the main source of klotho suggests that hormones and factors involved in mineral homeostasis play a role in this regulation