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The authors explain that the “reported wound-healing activity of TB-500 in literature may be due to its metabolite Ac-LKKTE rather than the parent form.”30 Additionally, there have been some positive preclinical research outcomes for the use of TB4 for hair growth,31 neuroprotection,32 tympanic membrane perforations,33 and decreasing mortality in sepsis, but more clinical research is needed before these potential benefits can be considered applicable to humans.5 Are TB4 and TB-500 safe

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Another commenter requested that CMS apply the informational-only feedback period policy to newly eligible MIPS clinicians or to clinicians who have not yet been scored on a particular measure