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PEGylation of peptides The majority of bioactive peptides exhibit limited aqueous solubility, insufficient structural stability, and rapid degradation, posing significant challenges to their pharmacological performance and clinical application

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1 H NMR (DMSO, 600 MHz): δ 2.38 (s, 9H), 5.74 (s, 6H), 8.34 (s, 3H)