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Researchers explored the effects of Cilostazol on a mouse model of Tau proteinopathy and found that Cilostazol significantly improved spatial learning and memory abilities in mice, that Cilostazol significantly increased the activity of the 26S proteasome, which reduced the accumulation of abnormal Tau proteins, and that this effect was closely linked to the cAMP/PKA pathway (Schaler and Myeku, 2018)

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There are no active IND applications or FDA-registered human clinical trials for BPC-157