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Role of Antioxidants during Chelation Induction of reactive oxygen species by metals and subsequent depletion of antioxidant cell defenses can result in disruption of the pro-oxidant/antioxidant balance in tissues [203]

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Antibody positivity was observed beginning on dosing day 14, and 1/24, 6/24, and 9/24 animals were determined as true positives on dosing day 14, dosing day 28, and recovery day 29, respectively (Fig