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OS also causes an accumulation of defective proteins in the endoplasmic reticulum, resulting in a phenomenon called the response to unfolded proteins (UPr), contributing to the process of autophagy leading to the production of proinflammatory interleukins (IL6 and IL8)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Ahn JH, Kim M, Park S, Jang W, Park J, Oh E, et al