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( b ) 13 C Lactate and ( c ) 13 C Glutamate enrichment in serum at time of tumour resection, in tumour tissue, and in adjacent edematous tissue, of seven (1-7) GBM patients injected with 13 C 6 -glucose

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However, this exchange can only provide short-term NADH/NAD + buffering and plays a minor role in NADH reoxidation